[Zinc-fans] SEA predictions
John J. Irwin
jji at cgl.ucsf.edu
Mon May 4 13:39:32 PDT 2009
Sorry, made a typo, change "out" to "one".
>> 2. What does pPvalue:10 mean?
> The p is as in -log10, so the P-value is 10^-10. This can be read as
> "you would expect to draw 10^10 molecules at random to find ONE that
> was as similar to the annotated compounds as this one is". Our cutoff
> for "interesting" SEA predictions is often 10^-10. Whereas this does
> not guarantee the ligand will be active, it is worth looking at.
More information about the Zinc-fans